Phase I: Anti-Parasitic Formula

Omphalia lapidescens

"Thunder ball fungus"

Anthelmintic:

Omphalin-a protease dissolves parasitic proteins creating an unfavorable parasitic environment for roundworms, hookworms, and tapeworms

Zhang, 2017

Sophora flavescens

"Evergreen shrub"

Probiotic:

Inhibits invasive microbes via 2 chemical components

Chen, 2018

Intestinal Anti-Inflammatory:

Downregulates IL-1b and IL-17

Chen, 2018

Torreya grandis

"Chinese nutmeg"

Anthelmintic:

Galangal acetate and miogadial terpenoid target TRP channels to inhibit parasite motility in roundworms

Liu, 2020

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Codonopsis spp.

"Bonnet Bellflower"

Red Blood Cell Stimulation:

Flavonoids that induce RBC generation by stimulating hematopoietic progenitors

Gao, 2018

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Quisqualis indicum L.

"Rangoon creeper"

Intestinal Anti-Inflammatory:

Polyphenols which inhibit prostaglandin synthesis

Sahu, 2012

Anthelmintic:

Corrosive to cuticle of roundworm, similar efficacy to mebendazole

Suter, 2017

Prunus mume

"Japanese apricot"

Antioxidant:

Phenolic acids with high level of scavenging and astringent actions

Liu, 2020

Functional liver support:

Regulates glucose and lipid regulation via hypothalamic leptin signaling

Liu, 2020

Prevents bacterial enteritis:

Neuraminidase with anti-Clostridial activity

Zingiber officinale

"Ginger root"

Anthelmintic:

Methanol extracts effective against Haemonchus contortus

Moazeni, 2011

Functional liver support:

6-gingerol prevents hepatic and renal oxidative stress

Joshi, 2017

Raphanus sativus

"Radish seed"

Prokinetic:

Histaminergic compounds promote gut motility and prevent bloat

Gilani, 2004

Intestinal anti-inflammatory:

Depresses IL-1b, TNF-a

Choi, 2016

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Atractylodes macrocephala

Aster root rhizome

Oxidative scavenger:

Reduces cell apoptosis in chronic ischemia/hypoxia

Hu, 2014

Prokinetic:

Enhances esophageal and small intestinal motility, reduces bloat

Emery, 2020

 Phase II: Gut Support Formula

Avena sativa

"Oatstraw"

Prebiotic:

Upregulates pathways that produce propionate and butyrate

Sargautiene, 2018

Curcurbita pepo

"Pumpkin seed"

Anthelmintic:

Berberine and palmitine depress egg hatching, larval development, and adult motility of strongyles

Gryzbek, 2016

Astragalus membranaceus

"Mongolian milkvetch"

Anti-inflammatory/Antioxidant:

Polysaccharies, flavonoids and saponins that are implicated in multiple anti-inflammatory and antioxidant pathways

Auyeung, 2016

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Withania somnifera

"Winter cherry"

Stress Reduction:

Sitoindosides VII-X and withaferin-A inhibit plasma corticosteroid levels, reduce frequency of gastric ulceration, increases ingestion and digestion in chronic stress models

Bhattacharya, 2003

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Althaea officinalis

"Marshmallow root"

Prohibits bacterial enteritis:

Causes dissolution of biofilms produced by Pasteurella aeruginosa

Aminnezhad, 2016

Urtica dioica

"Nettle leaf"

Intestinal immunity:

Flavonol glycosides and phenolic acids inhibit cyclooxygenase and lipoxygenase of platelets.

Increase monocyte chemoattractant protein-1 from intestinal epithelium, preserving epithelial integrity during disease states

Franciskovic, 2017

Medicago sativa

"Alfalfa leaf"

Anthelmintic/Anti-inflammatory:

Triterpene glycosides, phytosterols, saponins, and coumarins with various anthelmintic and anti-inflammatory effects. 

Rich in Ca, Phos, Mag, Potassium, Zinc and Iron

Bora, 2010

Centella asiatica

"Pennywort"

Wound Healing:

Saponins and tannins which improve wound healing during contracture stage. 

Reduces corticosterones in the thalamus and hippocampus during chronic stress conditions.

Gohil, 2010

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Foeniculum vulgare

"Fennel seeds"

Lactation Support:

Quercetin-3-O-galactoside imrpoves milk supply during lactation

Rather, 2016

Silybum marianum

"Milk Thistle seed"

Liver support:

Flavonolignans that work as antifibrotic during liver diseases and conditions causing liver injury

Abenavoli, 2018

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Calendula officinalis

"Marigold"

Anthelmintic:

Oleanolic acids cause mortality and L3 larva and reduces reproductive capacity for adult strongyles.

Al-Snafi, 2015

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