Phase I: Anti-Parasitic Formula
Omphalia lapidescens
"Thunder ball fungus"
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Anthelmintic:
Omphalin-a protease dissolves parasitic proteins creating an unfavorable parasitic environment for roundworms, hookworms, and tapeworms
Zhang, 2017
Sophora flavescens
"Evergreen shrub"
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Probiotic:
Inhibits invasive microbes via 2 chemical components
Chen, 2018
Intestinal Anti-Inflammatory:
Downregulates IL-1b and IL-17
Chen, 2018
Torreya grandis
"Chinese nutmeg"
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Anthelmintic:
Galangal acetate and miogadial terpenoid target TRP channels to inhibit parasite motility in roundworms
Liu, 2020
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Codonopsis spp.
"Bonnet Bellflower"
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Red Blood Cell Stimulation:
Flavonoids that induce RBC generation by stimulating hematopoietic progenitors
Gao, 2018
Quisqualis indicum L.
"Rangoon creeper"
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Intestinal Anti-Inflammatory:
Polyphenols which inhibit prostaglandin synthesis
Sahu, 2012
Anthelmintic:
Corrosive to cuticle of roundworm, similar efficacy to mebendazole
Suter, 2017
Prunus mume
"Japanese apricot"
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Antioxidant:
Phenolic acids with high level of scavenging and astringent actions
Liu, 2020
Functional liver support:
Regulates glucose and lipid regulation via hypothalamic leptin signaling
Liu, 2020
Prevents bacterial enteritis:
Neuraminidase with anti-Clostridial activity
Zingiber officinale
"Ginger root"
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Anthelmintic:
Methanol extracts effective against Haemonchus contortus
Moazeni, 2011
Functional liver support:
6-gingerol prevents hepatic and renal oxidative stress
Joshi, 2017
Raphanus sativus
"Radish seed"
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Prokinetic:
Histaminergic compounds promote gut motility and prevent bloat
Gilani, 2004
Intestinal anti-inflammatory:
Depresses IL-1b, TNF-a
Choi, 2016
Atractylodes macrocephala
Aster root rhizome
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Oxidative scavenger:
Reduces cell apoptosis in chronic ischemia/hypoxia
Hu, 2014
Prokinetic:
Enhances esophageal and small intestinal motility, reduces bloat
Emery, 2020
Phase II: Gut Support Formula
Avena sativa
"Oatstraw"
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Prebiotic:
Upregulates pathways that produce propionate and butyrate
Sargautiene, 2018
Curcurbita pepo
"Pumpkin seed"
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Anthelmintic:
Berberine and palmitine depress egg hatching, larval development, and adult motility of strongyles
Gryzbek, 2016
Astragalus membranaceus
"Mongolian milkvetch"
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Anti-inflammatory/Antioxidant:
Polysaccharies, flavonoids and saponins that are implicated in multiple anti-inflammatory and antioxidant pathways
Auyeung, 2016
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Withania somnifera
"Winter cherry"
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Stress Reduction:
Sitoindosides VII-X and withaferin-A inhibit plasma corticosteroid levels, reduce frequency of gastric ulceration, increases ingestion and digestion in chronic stress models
Bhattacharya, 2003
Althaea officinalis
"Marshmallow root"
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Prohibits bacterial enteritis:
Causes dissolution of biofilms produced by Pasteurella aeruginosa
Aminnezhad, 2016
Urtica dioica
"Nettle leaf"
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Intestinal immunity:
Flavonol glycosides and phenolic acids inhibit cyclooxygenase and lipoxygenase of platelets.
Increase monocyte chemoattractant protein-1 from intestinal epithelium, preserving epithelial integrity during disease states
Franciskovic, 2017
Medicago sativa
"Alfalfa leaf"
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Anthelmintic/Anti-inflammatory:
Triterpene glycosides, phytosterols, saponins, and coumarins with various anthelmintic and anti-inflammatory effects.
Rich in Ca, Phos, Mag, Potassium, Zinc and Iron
Bora, 2010
Centella asiatica
"Pennywort"
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Wound Healing:
Saponins and tannins which improve wound healing during contracture stage.
Reduces corticosterones in the thalamus and hippocampus during chronic stress conditions.
Gohil, 2010
Foeniculum vulgare
"Fennel seeds"
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Lactation Support:
Quercetin-3-O-galactoside imrpoves milk supply during lactation
Rather, 2016
Silybum marianum
"Milk Thistle seed"
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Liver support:
Flavonolignans that work as antifibrotic during liver diseases and conditions causing liver injury
Abenavoli, 2018
Calendula officinalis
"Marigold"
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Anthelmintic:
Oleanolic acids cause mortality and L3 larva and reduces reproductive capacity for adult strongyles.
Al-Snafi, 2015
